Picture of the month: Vegetal view of a reconstructed 128-cell Ciona gastrula. Muscle and mesenchyme are in red, endoderm in blue, notochord in orange, TLC in green, and A-line neural cells in yellow. Image communicated by F. Robin and P. Lemaire.
(Don't hesitate to send us your own pictures with a short description !)
|
| ANISEED news |
15/12/2009
 |
New articles:
|
Articles recently added to the database
If you are author of these articles, please check the annotation and don't hesitate to contact us if you have remarks.
|
15/12/2009
 |
New pages:
|
-
Upstream regulators page (eg otx regulation)
At the individual gene level, the "Upstream regulators tab" gives access to all genes regulating a gene of interest in the various territories across development.
For example, if the gene of interest is Otx, you can access to evidences indicating that Ci-FGF9/16/20 upregulates Ci-otx in b6.5 cell pair (2 evidences) and a6.5 cell pair (2 evidences) at 32-cell stage.
-
Downstream targets page (eg otx function)
The "Downstream targets tab" lists targets of the gene of interest by territories and stages.
For example, if the gene of interest is Otx, you can access to evidences indicating that Otx upregulates TWIST-like-b in A8.12 cell pair (1 evidence) A8.11 cell pair (1 evidence) B8.5 cell pair (1 evidence) B7.7 cell pair (1 evidence) at 112 cell stage.
-
Anatomy-regulation-card.php (eg A8.11)
At the individual territory level, the "anatomical gene network card" indicates the regulatory interactions that take place in this territory. It shows a table in which genes in the columns are regulated by genes in the rows.
|
09/03/2009
|
New:
|
Full ORF Gateway-compatible clones and KH transcript models are now accessible from the Aniseed website, in addition to their representation in the Aniseed Genome browser.
How access these information?
|
|
|
|
ANISEED version 3: A model organism database for Ciona intestinalis, Ciona savignyi, Halocynthia roretzi and Phallusia mammillata
|
|
Welcome to ANISEED version 3
Aniseed is a database designed to offer a representation of ascidian embryonic development at the level
of the genome (cis-regulatory sequences, spatial gene expression, protein annotation),
of the cell (cell shapes, fate, lineage) or of the whole embryo (anatomy, morphogenesis).
Currently, the anatomy of four organism models are represented in Aniseed: Ciona intestinalis,
Ciona savignyi, Halocynthia roretzi and Phallusia mammillata.
Extensive molecular data can be found for Halocynthia roretzi and Ciona intestinalis.
In particular, this version supports four sets of Ciona intestinalis transcript models: JGI v1.0,
KyotoGrail 2005, KH and ENSEMBL, all functionally annotated, and grouped into Aniseedv3.0 gene models.
You can explore gene expression profiles during normal or experimentally manipulated development,
access validated cis-regulatory regions, get the molecular tools used to assay gene function,
or all articles related to the function, or regulation of a given gene.
Known transcriptional regulators and targets are listed for each gene,
as are the gene regulatory networks acting in individual anatomical territories.
The archived ANISEED v2.0 can still be accessed from the "about" tab of the menu.
Have fun and as usual, please send us feedback on this version at aniseed@ibdm.univ-mrs.fr.
The aniseed team
|
If you don't know where to start ... Use anisearch to perform a keyword search on the whole database except cDNA clones, which can be accessed via the "genes/clones" menu at the top of the page.
eg. "otx" retrieves all data associated to otx. You can also combine words for example "otx 32 cell a6.5" will retrieve all in situs for otx at the 32 cell stage showing staining in the a6.5 blastomere.
|
Aniseed V2.0 - Archive
Aniseed in its previous version is still available by clicking Aniseed V2.0
Virtual embryo
The 3D Virtual embryo is available to download in the download section of the website.
It's well supported on the majority of platform (MacOS, Windows, Linux).
Download
All the data present in our website are now freely downloadable (Insitu data, clones, anatomical ontologies, ...) Visit our download page for more informations.
Tutorials
Many tutorials (text and movies) are online and may be useful ...
MISFISHIE Exchange Format
In Situs Exchange Format used by ANISEED.
|
|